The early diagnosis of muscular dystrophy may be very difficult and the later less common forms may pose many diagnostic problems to the clinician. Serum creatine phosphokinase activity appears to be a valuable laboratory test to aid in the diagnosis of muscle disease. In determinations on serum from 200 patients with muscular disorders, the concentration of this enzyme was found to be increased only in patients with progressive muscular dystrophy or dermatomyositis.
Bibliographical noteFunding Information:
From the Departments o\[ Physical Medicine, Neurology, and Pediatrics o\[ the University of Minnesota. This study was supported by the Vocational Rehabilitation Administration Grant RT-2.