The use of mouse chromosome substitution strains to investigate the genetic regulation of pubertal timing

Brandon M. Nathan, Craig A. Hodges, Mark R. Palmert

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

Identification of genes underlying complex traits such as pubertal timing, is vital to our understanding of fundamental human developmental processes. Animal models can provide an important adjunct to more traditional human investigations. Within this review, we discuss the use and advantages of chromosome substitution strains in the investigation of factors that regulate the timing of the onset of puberty.

Original languageEnglish (US)
Pages (from-to)103-108
Number of pages6
JournalMolecular and Cellular Endocrinology
Volume254-255
DOIs
StatePublished - Jul 25 2006

Keywords

  • Genetic regulation
  • Mouse models
  • Pubertal timing

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