Abstract
In recent years, the use of perfusion-fixed cadaveric specimens and isolated heart models has helped to develop an improved understanding of the device-tissue interface and has also contributed to the rapid evolution of surgically and percutaneously delivered cardiac therapies. This chapter describes a novel series of techniques utilized within the Visible Heart® laboratory by engineers, scientists, and anatomists to visualize and analyze the heart and assess potential repair or replacement therapies. The study of reanimated large mammalian hearts (including human hearts) and specially prepared anatomical specimens, using various clinical and nonclinical imaging modalities, has provided feedback for design engineers and clinicians that seek to develop and/or employ cardiac therapies for patients with acquired or congenital heart disease.
Original language | English (US) |
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Title of host publication | Handbook of Cardiac Anatomy, Physiology, and Devices, Third Edition |
Publisher | Springer International Publishing |
Pages | 751-764 |
Number of pages | 14 |
ISBN (Electronic) | 9783319194646 |
ISBN (Print) | 9783319194639 |
DOIs | |
State | Published - Jan 1 2015 |
Keywords
- Cardiac device design and development
- Human cardiac anatomy
- Isolated heart model
- Reanimated heart