The use of isolated heart models and anatomical specimens as means to enhance the design and testing of cardiac devices

Michael G Bateman, Michael D. Eggen, Julianne H. Spencer, Tinen L Iles, Paul A Iaizzo

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

In recent years, the use of perfusion-fixed cadaveric specimens and isolated heart models has helped to develop an improved understanding of the device-tissue interface and has also contributed to the rapid evolution of surgically and percutaneously delivered cardiac therapies. This chapter describes a novel series of techniques utilized within the Visible Heart® laboratory by engineers, scientists, and anatomists to visualize and analyze the heart and assess potential repair or replacement therapies. The study of reanimated large mammalian hearts (including human hearts) and specially prepared anatomical specimens, using various clinical and nonclinical imaging modalities, has provided feedback for design engineers and clinicians that seek to develop and/or employ cardiac therapies for patients with acquired or congenital heart disease.

Original languageEnglish (US)
Title of host publicationHandbook of Cardiac Anatomy, Physiology, and Devices, Third Edition
PublisherSpringer International Publishing
Pages751-764
Number of pages14
ISBN (Electronic)9783319194646
ISBN (Print)9783319194639
DOIs
StatePublished - Jan 1 2015

Keywords

  • Cardiac device design and development
  • Human cardiac anatomy
  • Isolated heart model
  • Reanimated heart

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