The use of alvimopan for postoperative ileus in small and large bowel resections

Justin T. Brady, Eslam M.G. Dosokey, Benjamin P. Crawshaw, Scott R. Steele, Conor P. Delaney

Research output: Contribution to journalReview articlepeer-review

8 Scopus citations

Abstract

Transient ileus is a normal physiologic process after surgery. When prolonged, it is an important contributor to postoperative complications, increased length of stay and increased healthcare costs. Efforts have been made to prevent and manage postoperative ileus; alvimopan is an oral, peripheral-opioid receptor antagonist, and the only currently US FDA-approved medication to accelerate the return of gastrointestinal function postoperatively.

Original languageEnglish (US)
Pages (from-to)1351-1358
Number of pages8
JournalExpert Review of Gastroenterology and Hepatology
Volume9
Issue number11
DOIs
StatePublished - Nov 2 2015

Keywords

  • alvimopan
  • bowel resection
  • laparoscopy
  • postoperative ileus
  • μ-opioid antagonist

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