Abstract
Transient ileus is a normal physiologic process after surgery. When prolonged, it is an important contributor to postoperative complications, increased length of stay and increased healthcare costs. Efforts have been made to prevent and manage postoperative ileus; alvimopan is an oral, peripheral-opioid receptor antagonist, and the only currently US FDA-approved medication to accelerate the return of gastrointestinal function postoperatively.
Original language | English (US) |
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Pages (from-to) | 1351-1358 |
Number of pages | 8 |
Journal | Expert Review of Gastroenterology and Hepatology |
Volume | 9 |
Issue number | 11 |
DOIs | |
State | Published - Nov 2 2015 |
Keywords
- alvimopan
- bowel resection
- laparoscopy
- postoperative ileus
- μ-opioid antagonist