The use of 18F-FDG PET ratios in the differential diagnosis of common malignant brain tumors

Kaan Meric, Ronan P. Killeen, Alain S. Abi-Ghanem, Fatima Soliman, Fuad Novruzov, Esin Cakan, Zuzan Cayci

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

Objective: This study examined the use of positron emission tomography (PET) ratios to improve the diagnostic ability of 18F-FDG PET/computed tomography (CT) in the differentiation of enhancing brain metastases, central nervous system lymphomas, and gliomas. Materials and methods: Seventy-six patients with malignant brain tumors and available magnetic resonance imaging and PET/CT examinations were included. Results: Among standardized uptake value (SUV)-related parameters tested, tumor maximum SUV to ipsilateral cortex maximum SUV ratio (Tmax:WMimax) and maximum SUV (SUVmax) proved to be the two most valuable parameters for differential diagnosis. Conclusion: In addition to SUVmax, Tmax:WMimax also seems to provide helpful information for the differential diagnosis of lymphomas from other malignant brain tumors.

Original languageEnglish (US)
Pages (from-to)970-974
Number of pages5
JournalClinical Imaging
Volume39
Issue number6
DOIs
StatePublished - Nov 2015

Bibliographical note

Publisher Copyright:
© 2015 Elsevier Inc.

Keywords

  • 18F-FDG positron emission tomography
  • Brain metastasis
  • Central nervous system lymphoma
  • Differential diagnosis
  • Glioma

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