The unique lipid composition of gecko (Gekko Gekko) photoreceptor outer segment membranes

Ching Yuan, Huiming Chen, Robert E. Anderson, Osamu Kuwata, Thomas G. Ebrey

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

This study investigated the lipid and fatty acid composition of gecko photoreceptor outer segment membranes which contain the P521 cone-type pigment. The lipids of gecko photoreceptor outer segment membranes were first extracted and separated by thin layer chromatography (TLC) and then analyzed by gas chromatography (GC). Our results show that gecko photoreceptor outer segment membranes contain less phosphatidylethanolamine (PE) and more phosphatidylcholine (PC) and phosphatidylserine (PS) compared with those of bovine and frog. The content of the polyunsaturated fatty acid, docosahexaenoic acid (DHA), in PC and PS is also the highest yet reported (55 and 63%, respectively). These lipid differences may provide some insight into the specific lipid requirements of cone-type pigments. Copyright (C) 1998 Elsevier Science Inc.

Original languageEnglish (US)
Pages (from-to)785-789
Number of pages5
JournalComparative Biochemistry and Physiology - B Biochemistry and Molecular Biology
Volume120
Issue number4
DOIs
StatePublished - Dec 1 1998

Keywords

  • Cell membrane
  • Cone-type visual pigment
  • Docosahexaenoic acid
  • Gecko
  • Lipid composition
  • Phospholipid
  • Photoreceptor
  • Retina

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