The type III TGF-β receptor signals through both Smad3 and the p38 MAP kinase pathways to contribute to inhibition of cell proliferation

Keyphrases

• P38 MAP Kinase 100%
• TGF-1 100%
• Mitogen-activated Protein Kinase 100%
• Cell Proliferation Inhibition 100%
• Smad3 100%
• Transforming Growth Factor Receptor 100%
• Transforming Growth Factor-β 80%
• Proliferation Inhibition 80%
• Cytoplasmic Domain 60%
• Growth Inhibition 40%
• Mediated Growth 40%
• MAPK Inhibitors 40%
• L6 Myoblasts 40%
• Cell Proliferation 20%
• Negative Regulator 20%
• Nuclear Localization 20%
• Additive Effect 20%
• Knockdown 20%
• Short Hairpin RNA (shRNA) 20%
• Dominant Negative 20%
• Co-receptor 20%
• Reporter Gene 20%
• P38 Phosphorylation 20%
• P38 Mitogen-activated Protein Kinase (p38 MAPK) 20%
• SB203580 20%
• Smad2 Phosphorylation 20%
• SB431542 20%
• Human Epithelial Cells 20%
• Basal Growth 20%
• Smad3 Phosphorylation 20%
• Ligand Presentation 20%
• Primary Epithelial Cells 20%
• RNA-based 20%

Biochemistry, Genetics and Molecular Biology

• Cell Proliferation 100%
• Growth Factor Receptor 100%
• Cancer Growth Factor 100%
• P38 Mitogen-Activated Protein Kinases 100%
• Growth Inhibition 28%
• Co-Receptor 14%
• Phosphotransferase 14%
• Kinase 14%
• Reporter Gene 14%
• Small Hairpin RNA 14%
• Small Interfering RNA 14%

Immunology and Microbiology

• Cell Proliferation 100%
• Cancer Growth Factor 100%
• Myoblast 28%
• Growth Inhibition 28%
• Mitogen 14%
• Reporter Gene 14%
• Ribonucleic Acid 14%
• Additive Effect 14%