The turkey prolactin-encoding gene and its regulatory region

Kiyoto Kurima; John A. Proudman; Mohamed E. El Halawani; Eric A. Wong

doi:10.1016/0378-1119(95)00032-2

The turkey prolactin-encoding gene and its regulatory region

Kiyoto Kurima, John A. Proudman, Mohamed E. El Halawani, Eric A. Wong

Animal Science

Research output: Contribution to journal › Article › peer-review

28 Scopus citations

Abstract

Overlapping prolactin (Prl) λ clones were isolated from a turkey genomic library. The 6.7-kb turkey Prl gene consists of five exons. Major transcription start points were located by primer extension 51-53 nucleotides upstream from the Met start codon. No estrogen response element (ERE) was found, but two regions similar to mammalian Pit-1/GHF-1-binding sites were identified by computer analysis. This suggests that transcription of the turkey Prl gene may be regulated by Pit-1/GHF-1, and not by the estrogen receptor.

Original language	English (US)
Pages (from-to)	309-310
Number of pages	2
Journal	Gene
Volume	156
Issue number	2
DOIs	https://doi.org/10.1016/0378-1119(95)00032-2
State	Published - Apr 24 1995

Keywords

Genomic library
Pit-1/GHF-1-binding sites
estrogen response element

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10.1016/0378-1119(95)00032-2

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title = "The turkey prolactin-encoding gene and its regulatory region",

abstract = "Overlapping prolactin (Prl) λ clones were isolated from a turkey genomic library. The 6.7-kb turkey Prl gene consists of five exons. Major transcription start points were located by primer extension 51-53 nucleotides upstream from the Met start codon. No estrogen response element (ERE) was found, but two regions similar to mammalian Pit-1/GHF-1-binding sites were identified by computer analysis. This suggests that transcription of the turkey Prl gene may be regulated by Pit-1/GHF-1, and not by the estrogen receptor.",

keywords = "Genomic library, Pit-1/GHF-1-binding sites, estrogen response element",

author = "Kiyoto Kurima and Proudman, {John A.} and {El Halawani}, {Mohamed E.} and Wong, {Eric A.}",

year = "1995",

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doi = "10.1016/0378-1119(95)00032-2",

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T1 - The turkey prolactin-encoding gene and its regulatory region

AU - Kurima, Kiyoto

AU - Proudman, John A.

AU - El Halawani, Mohamed E.

AU - Wong, Eric A.

PY - 1995/4/24

Y1 - 1995/4/24

N2 - Overlapping prolactin (Prl) λ clones were isolated from a turkey genomic library. The 6.7-kb turkey Prl gene consists of five exons. Major transcription start points were located by primer extension 51-53 nucleotides upstream from the Met start codon. No estrogen response element (ERE) was found, but two regions similar to mammalian Pit-1/GHF-1-binding sites were identified by computer analysis. This suggests that transcription of the turkey Prl gene may be regulated by Pit-1/GHF-1, and not by the estrogen receptor.

AB - Overlapping prolactin (Prl) λ clones were isolated from a turkey genomic library. The 6.7-kb turkey Prl gene consists of five exons. Major transcription start points were located by primer extension 51-53 nucleotides upstream from the Met start codon. No estrogen response element (ERE) was found, but two regions similar to mammalian Pit-1/GHF-1-binding sites were identified by computer analysis. This suggests that transcription of the turkey Prl gene may be regulated by Pit-1/GHF-1, and not by the estrogen receptor.

KW - Genomic library

KW - Pit-1/GHF-1-binding sites

KW - estrogen response element

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VL - 156

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JO - Gene

JF - Gene

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ER -

The turkey prolactin-encoding gene and its regulatory region

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