The turkey prolactin-encoding gene and its regulatory region

Kiyoto Kurima, John A. Proudman, Mohamed E. El Halawani, Eric A. Wong

Research output: Contribution to journalArticlepeer-review

27 Scopus citations

Abstract

Overlapping prolactin (Prl) λ clones were isolated from a turkey genomic library. The 6.7-kb turkey Prl gene consists of five exons. Major transcription start points were located by primer extension 51-53 nucleotides upstream from the Met start codon. No estrogen response element (ERE) was found, but two regions similar to mammalian Pit-1/GHF-1-binding sites were identified by computer analysis. This suggests that transcription of the turkey Prl gene may be regulated by Pit-1/GHF-1, and not by the estrogen receptor.

Original languageEnglish (US)
Pages (from-to)309-310
Number of pages2
JournalGene
Volume156
Issue number2
DOIs
StatePublished - Apr 24 1995

Keywords

  • Genomic library
  • Pit-1/GHF-1-binding sites
  • estrogen response element

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