The synthesis of enantiomers of 4-ketocyclophosphamide

K. Misiura, K. Pankiewicz, W. J. Stec, M. Jarman

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

Oxidation with Fenton's reagent and by direct ozonation of the enantiomers of the antitumour agent cyclophosphamide afforded optically pure enantiomers of 4-ketocyclophosphamide. Oxidation with potassium permanganate, however, gave the corresponding racemate.

Original languageEnglish (US)
Pages (from-to)216-217
Number of pages2
JournalExperientia
Volume37
Issue number3
DOIs
StatePublished - Mar 1981

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