The Spinocerebellar Ataxia 8 noncoding RNA causes neurodegeneration and associates with Staufen in Drosophila

Keyphrases

• Non-coding RNA (ncRNA) 100%
• Neurodegeneration 100%
• Drosophilidae 100%
• Spinocerebellar Ataxia Type 8 (SCA8) 100%
• RNA-binding Protein 16%
• Repeat Expansion 16%
• Genetic Modifiers 8%
• Neurodegenerative 8%
• Human Disease 8%
• Therapeutic Intervention 8%
• Neurodegenerative Diseases 8%
• Neuronal Survival 8%
• Gene Products 8%
• Specific Mechanisms 8%
• Progressive Neurodegeneration 8%
• Late-onset 8%
• Interaction Strength 8%
• Normal Function 8%
• Predicted Genes 8%
• Triplet Repeat Expansion 8%
• Interaction Domains 8%
• Genetic Modifier Screen 8%
• Drosophila Retina 8%
• Muscleblind 8%
• Domain Map 8%

Biochemistry, Genetics and Molecular Biology

• Non-Coding RNA 100%
• Genetics 66%
• RNA-binding Protein 66%
• RNA 33%
• Wild Type 33%
• Gene Product 33%

Neuroscience

• Non-Coding RNA 100%
• Spinocerebellar Ataxia 100%
• Neurodegeneration 100%
• RNA-binding Protein 16%
• Neurodegenerative Disorder 8%
• Gene Product 8%