The spectrum of peripheral neuropathy associated with ARC and AIDS

Robert G. Miller, Gareth J. Parry, Wolfgang Pfaeffl, William Lang, Randolph Lippert, Dobri Kiprov

Research output: Contribution to journalArticlepeer-review

72 Scopus citations


Peripheral neuropathy is increasingly recognized as a complication of the Aquired Immune Deficiency Syndrome (AIDS) and AIDS‐related complex (ARC), but the varied clinical features have been incompletely described. Thirty homosexual men with peripheral neuropathy were evaluated in this study. Twenty‐one had ARC and nine had AIDS. Four distinct clinical syndromes were recognized: distal sensorimotor polyneuropathy, chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), mononeuropathy multiplex, and progressive polyradiculopathy. Four patients with clinical, electrophysiologic, and histologic evidence of CIDP and severe progressive weakness improved with plasma exchange, three regaining normal function.

Original languageEnglish (US)
Pages (from-to)857-863
Number of pages7
JournalMuscle & Nerve
Issue number8
StatePublished - Aug 1988


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