The S RNA segment of lymphocytic choriomeningitis virus codes for the nucleoprotein and glycoproteins 1 and 2

Y. Riviere, R. Ahmed, P. J. Southern, M. J. Buchmeier, F. J. Dutko, M. B. Oldstone

Research output: Contribution to journalArticlepeer-review

57 Scopus citations

Abstract

The lymphocytic choriomeningitis virus (LCMV) genome consists of a large RNA segment and a small RNA segment. The three major structural proteins of this virus are an internal nucleoprotein and two surface glycoproteins. Intertypic reassortants between the Armstrong and WE strains of LCMV were made to map proteins encoded by the LCM genome segments. Using monoclonal antibodies specific for the nucleoprotein and the glycoproteins of WE and Armstrong, we showed that the small RNA segment of LCMV codes for the three major structural polypeptides.

Original languageEnglish (US)
Pages (from-to)966-968
Number of pages3
JournalJournal of virology
Volume53
Issue number3
DOIs
StatePublished - 1985

Fingerprint Dive into the research topics of 'The S RNA segment of lymphocytic choriomeningitis virus codes for the nucleoprotein and glycoproteins 1 and 2'. Together they form a unique fingerprint.

Cite this