The role of tissue repair and leukocytes in the pathogenesis of emphysema

J. R. Hoidal, Dennis E Niewoehner

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

The results of the study suggest that the same lung injury might result in either emphysema or fibrosis, connective tissue synthesis during the healing phase being the critical determinant. Furthermore, in the model described, neutrophils do not appear to be essential mediators of the emphysema which developed. We suggest that common lung toxins, such as cigarette smoke, may have important effects upon the healing phase after injury.

Original languageEnglish (US)
Pages (from-to)58S-59S
JournalCHEST
Volume83
Issue number5 Suppl.
DOIs
StatePublished - Jan 1 1983

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