The role of the veterinarian in genetic counseling.

M. T. McNeil, F. A. Ponce de Leon

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations

Abstract

When the veterinarian encounters a disorder with an unknown etiology, the following criteria can identify the potential contribution of the animals genome to the problem: 1. The disorder occurs with higher frequency in a group of related animals than in the general population. 2. A defect involves the same anatomic site in a group of related animals. 3. The disease has a consistent age of onset and clinical course. 4. The disease increases in frequency with inbreeding. 5. The disorder is consistently associated with a specific chromosomal anomaly. 6. The disorder can be traced to an abnormality in a single specific protein molecule. Veterinarians must access the information that knowledgeable breeders gather and channel that information constructively into diagnostic tests, test breedings, and data banks to work toward a common goal--discovery of the genetic basis of disease and development of appropriate breeding programs to minimize or eliminate debilitating genetic problems in dogs.

Original languageEnglish (US)
Pages (from-to)471-490
Number of pages20
JournalProblems in veterinary medicine
Volume4
Issue number3
StatePublished - Sep 1992

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