The role of spacers on the self-assembly of DNA aptamer-amphiphiles into micelles and nanotapes

Timothy R Pearce, Brett Waybrant, Efie Kokkoli

Research output: Contribution to journalArticlepeer-review

18 Scopus citations

Abstract

The self-assembly of single-stranded DNA (ssDNA) aptamer-amphiphiles was influenced by the choice of spacer used to link the hydrophobic tail and aptamer headgroup. Aptamer-amphiphiles without spacers or with hydrophilic spacers formed globular micelles while amphiphiles with hydrophobic spacers formed bilayer nanotapes, which are the first such structures formed by DNA-amphiphiles.

Original languageEnglish (US)
Pages (from-to)210-212
Number of pages3
JournalChemical Communications
Volume50
Issue number2
DOIs
StatePublished - Nov 28 2014

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