There are many brain proteins that participate in the early growth and development of the mammalian central nervous system. Reelin is a glycoprotein that helps guide brain development in an orderly fashion. Changes in the level of this protein or its receptors or downstream proteins may cause abnormal corticogenesis and alter synaptic plasticity. These changes have also been observed in a number of neuropsychiatric disorders. We will discuss more about this protein and its possible involvement in various neuropsychiatric disorders.
|Original language||English (US)|
|Title of host publication||Reelin Glycoprotein|
|Subtitle of host publication||Structure, Biology and Roles in Health and Disease|
|Publisher||Springer New York|
|Number of pages||23|
|State||Published - Jan 1 2008|