The role of Reelin in etiology and treatment of psychiatric disorders

S H Fatemi, Teri J. Reutiman, Timothy D. Folsom

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Scopus citations

Abstract

There are many brain proteins that participate in the early growth and development of the mammalian central nervous system. Reelin is a glycoprotein that helps guide brain development in an orderly fashion. Changes in the level of this protein or its receptors or downstream proteins may cause abnormal corticogenesis and alter synaptic plasticity. These changes have also been observed in a number of neuropsychiatric disorders. We will discuss more about this protein and its possible involvement in various neuropsychiatric disorders.

Original languageEnglish (US)
Title of host publicationReelin Glycoprotein
Subtitle of host publicationStructure, Biology and Roles in Health and Disease
PublisherSpringer New York
Pages317-339
Number of pages23
ISBN (Electronic)9780387767611
ISBN (Print)9780387767604
DOIs
StatePublished - Jan 1 2008

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