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The role of PGC1α in cancer metabolism and its therapeutic implications
Zheqiong Tan
, Xiangjian Luo
, Lanbo Xiao
, Min Tang
,
Ann M. Bode
, Zigang Dong
, Ya Cao
The Hormel Institute
Research output
:
Contribution to journal
›
Review article
›
peer-review
168
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Scopus citations
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Keyphrases
In Cancer
100%
Therapeutic Implications
100%
Cancer Metabolism
100%
Peroxisome Proliferator-activated Receptor-γ coactivator-1α (PGC-1α)
100%
Cancer Cells
23%
Transcription Factor
15%
Coactivator
15%
Controller
7%
Fatty Acid Metabolism
7%
Chemotherapy
7%
Cancer Development
7%
Chronic Disease
7%
Tumor Metastasis
7%
Cancer Cell Survival
7%
Oncogene
7%
Nutrient Deprivation
7%
Therapeutic Treatment
7%
Microenvironment
7%
Defense System
7%
Oxidative Damage
7%
Metabolic Homeostasis
7%
Reactive Oxygen Species
7%
Abnormal Expression
7%
Molecular Therapy
7%
Mitochondrial Respiration
7%
Molecular Classification
7%
Cancer Types
7%
Metabolic Activity
7%
Specific Transcription Factor
7%
Resistant Cancer Cells
7%
Metabolic Adaptation
7%
Re-sensitizing
7%
Cell Tumor
7%
Promising Target
7%
Signaling Axis
7%
Characteristic Traits
7%
Stress Sensor
7%
Cellular Metabolic
7%
Metabolic Pathways
7%
Biochemistry, Genetics and Molecular Biology
Metabolic Pathway
100%
Cancer Cell
100%
Transcription Factors
60%
Oncogene
20%
Fatty Acid Metabolism
20%
Mitochondrial Respiration
20%
Microphthalmia-Associated Transcription Factor
20%
Homeostasis
20%
Cell Survival
20%
Peroxisome Proliferator-Activated Receptor
20%
Polymorphonuclear Cell
20%