Abstract
Autism is a neurodevelopmental disorder with both genetic and environmental etiologies. Prenatal infections may play a role in evolution of autism. Experimental evidence shows human influenza viral infection in pregnancy leads to significant deleterious effects in brain structure and function in the developing mouse progeny. Several brain genes of interest in this animal model are also involved in the pathology of autism. The roles of these genes in brain development are discussed in this review.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 177-182 |
| Number of pages | 6 |
| Journal | American Journal of Biochemistry and Biotechnology |
| Volume | 4 |
| Issue number | 2 |
| DOIs | |
| State | Published - 2008 |
Keywords
- Autism
- Brain genes
- Influenza
- Mouse
- Viral model
