The role of neurodevelopmental genes in infectious etiology of autism

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations

Abstract

Autism is a neurodevelopmental disorder with both genetic and environmental etiologies. Prenatal infections may play a role in evolution of autism. Experimental evidence shows human influenza viral infection in pregnancy leads to significant deleterious effects in brain structure and function in the developing mouse progeny. Several brain genes of interest in this animal model are also involved in the pathology of autism. The roles of these genes in brain development are discussed in this review.

Original languageEnglish (US)
Pages (from-to)177-182
Number of pages6
JournalAmerican Journal of Biochemistry and Biotechnology
Volume4
Issue number2
DOIs
StatePublished - 2008

Keywords

  • Autism
  • Brain genes
  • Influenza
  • Mouse
  • Viral model

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