The role of fluid hydrostatic pressure in bone-implant interface load transfer

Jack L. Lewis, Cary Keller, S. David Stulberg, John Steege, Michael Santare

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Permeability of the soft tissue-bone system surrounding artificial joints fixed in cancellous bone was measured in four adult dogs after implants had been in place 2 months. Fluid was forced through a cavity formed by removal of the implant, the cavity was capped with a stopper to allow for pressure generation. Surface permeability of the 2-month-old implant cavity was 45 times less than the permeability of freshly drilled holes in cancellous bone. A mathematical model of a rigid implant resting on a biphasic solid-fluid layer showed the fluid carried 90% of the load when the implant cavity permeability was assumed, but only 27% when the freshly drilled permeability was used. The results suggest caution in interpreting finite-element models with bonded interfaces and suggest a possible role of the fluid in biological response at the interface.

Original languageEnglish (US)
Pages (from-to)559-571
Number of pages13
JournalAnnals of Biomedical Engineering
Issue number6
StatePublished - Nov 1984


  • Fluid
  • Implant
  • Interface


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