TY - JOUR
T1 - The role of clusterin in tissue injury.
AU - Silkensen, J. R.
AU - Schwochau, G. B.
AU - Rosenberg, M. E.
PY - 1994
Y1 - 1994
N2 - Clusterin is a widely distributed glycoprotein with a wide range of biologic properties. A prominent and defining feature of clusterin is its marked induction in such disease states as glomerulonephritis, cystic renal disease, renal tubular injury, neurodegenerative conditions, atherosclerosis, and myocardial infarction. The expression of clusterin in these states is intriguing given the apparent incongruity of the conditions listed, the variety of stimuli eliciting such expression, and the multiple proposed roles once induced. This review will outline the conditions associated with clusterin induction and speculate on its role in disease.
AB - Clusterin is a widely distributed glycoprotein with a wide range of biologic properties. A prominent and defining feature of clusterin is its marked induction in such disease states as glomerulonephritis, cystic renal disease, renal tubular injury, neurodegenerative conditions, atherosclerosis, and myocardial infarction. The expression of clusterin in these states is intriguing given the apparent incongruity of the conditions listed, the variety of stimuli eliciting such expression, and the multiple proposed roles once induced. This review will outline the conditions associated with clusterin induction and speculate on its role in disease.
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U2 - 10.1139/o94-065
DO - 10.1139/o94-065
M3 - Review article
C2 - 7654321
AN - SCOPUS:0028537112
SN - 0829-8211
VL - 72
SP - 483
EP - 488
JO - Biochemistry and cell biology = Biochimie et biologie cellulaire
JF - Biochemistry and cell biology = Biochimie et biologie cellulaire
IS - 11-12
ER -
