Abstract
Glycogen synthetase D phosphatase catalyzes the conversion of synthetase D to synthetase I. The phosphatase reaction has been found to be inhibited by ATP, ADP and UDP; however, only ATP inhibited at a physiological concentration. ATP inhibition was enhanced by glycogen. Glucose 6-phosphate (G 6-P) stimulated the phosphatase reaction and at least partially relieved the ATP inhibition. A possible physiological role for ATP, G 6-P and glycogen in the regulation of the synthetase D phosphatase reaction has been proposed.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 898-906 |
| Number of pages | 9 |
| Journal | Biochemical and Biophysical Research Communications |
| Volume | 48 |
| Issue number | 4 |
| DOIs | |
| State | Published - Aug 21 1972 |
Bibliographical note
Funding Information:thanks to Mrs. Carol Reynolds This work supported in part by
Copyright:
Copyright 2014 Elsevier B.V., All rights reserved.