The RISE FOR HEALTH study: Methods for in-person musculoskeletal assessment

For the Prevention of Lower Urinary Tract Symptoms (PLUS) Research Consortium

Research output: Contribution to journalArticlepeer-review


Objectives: To describe the methods for the in-person musculoskeletal (MSK) assessment of the RISE FOR HEALTH (RISE) study, a population-based multicenter prospective cohort study designed to identify factors associated with bladder health (BH) conducted by the Prevention of Lower Urinary Tract Symptoms Research Consortium (PLUS). Methods: A subset of RISE participants who express interest in the in-person assessment are screened to ensure eligibility (planned n = 525). Eligible consenting participants are asked to complete a standardized MSK assessment to evaluate core stability (four component core stability test, lumbar spine pain (seated slump test), pelvic girdle pain, (sacroiliac joint, anterior superior iliac spine, pubic symphysis tenderness, and pelvic girdle pain provocation test), hip pain (flexion, abduction, internal rotation and flexion, adduction and external rotation) and pelvic girdle function (active straight leg raise). Participants are also asked to complete the Short Physical Performance Battery to measure balance, gait speed, lower extremity strength, and functional capacity. Results: Detailed online and in-person MSK training sessions led by physical therapy were used to certify research staff at each clinical center before the start of RISE in-person assessments. All evaluators exceeded the pre-specified pass rates. Conclusions: The RISE in-person MSK assessment will provide further insight into the role of general body MSK health and dysfunction and the spectrum of BH.

Original languageEnglish (US)
JournalNeurourology and Urodynamics
StateAccepted/In press - 2022

Bibliographical note

Funding Information:
This work was supported by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) at the National Institutes of Health (NIH) by cooperative agreements (U24 DK106786, U01 DK106853, U01 DK126045, U01 DK106858, U01 DK106898, U01 DK106893, U01 DK106827, U01 DK106908, and U01 DK106892). The content of this article is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. Additional funding from the National Institute on Aging, NIH Office of Research on Women's Health. The authors gratefully acknowledge the collegial research work of the Prevention of Lower Urinary Tract Symptoms (PLUS) Research Consortium members. members including RCs and lead PT Betsy Walts, PT, OCS, MCS, Cert MDT, M Health Fairview Sports and Physical Therapy Rehabilitation. Loyola University Chicago—Maywood, IL (U01DK106898)—Multi‐Principal Investigators: Linda Brubaker, MD; Elizabeth R. Mueller, MD, MSME; Investigators: Marian Acevedo‐Alvarez, MD; Colleen M. Fitzgerald, MD, MS; Cecilia T. Hardacker, MSN, RN, CNL; Jeni Hebert‐Beirne, PhD, MPH. Missy Lavender, MBA. Northwestern University–Chicago IL (U01DK126045)—Multi‐Principal Investigators: James W. Griffith, PhD; Kimberly Sue Kenton, MD; Melissa Simon, MD, MPH; Investigator: Julia Geynisman‐Tan, MD. University of Alabama at Birmingham–Birmingham, AL (U01DK106858)—Principal Investigator: Alayne D. Markland, DO, MSc; Investigators: Tamera Coyne‐Beasley, MD, MPH, FAAP, FSAHM; Kathryn L. Burgio, PhD; Cora E. Lewis, MD, MSPH; Gerald McGwin, Jr., MS, PhD; Camille P. Vaughan, MD, MS; Beverly Rosa Williams, PhD. University of California San Diego–La Jolla, CA (U01DK106827)—Principal Investigator: Emily S. Lukacz, MD; Investigators: Sheila Gahagan, MD, MPH; D. Yvette LaCoursiere, MD, MPH; Jesse Nodora, DrPH. University of Michigan ‐ Ann Arbor, MI (U01DK106893)—Principal Investigator: Janis M. Miller, PhD, APRN, FAAN; Investigator: Lisa Kane Low, PhD, CNM, FACNM, FAAN. University of Minnesota (Scientific and Data Coordinating Center)–Minneapolis MN (U24DK106786)—Multi‐Principal Investigators: Bernard L. Harlow, PhD; Kyle D. Rudser, PhD; Investigators: Sonya S. Brady, PhD; Haitao Chu, MD, PhD; Cynthia S. Fok, MD, MPH; Peter Scal, PhD; Todd Rockwood, PhD. University of Pennsylvania–Philadelphia, PA (U01DK106892)—Principal Investigator: Multi‐Principal Investigators: Diane K. Newman, DNP FAAN; Ariana L. Smith, MD; Investigators: Amanda Berry, MSN, CRNP; Heather Klusaritz, PhD, MSW; Ann E. Stapleton, MD; Jean F. Wyman, PhD. Washington University in St. Louis–Saint Louis, MO (U01DK106853)—Principal Investigator: Siobhan Sutcliffe, PhD, ScM, MHS; Investigators: Aimee S. James, PhD, MPH; Jerry L. Lowder, MD, MSc; Melanie R. Meister, MD, MSCI. Yale University–New Haven, CT (U01DK106908)—Principal Investigator: Leslie M. Rickey, MD, MPH; Investigators: Marie A. Brault, PhD; Deepa R. Camenga, MD, MHS; Shayna D. Cunningham, PhD. Steering Committee Chair: Linda Brubaker, MD. UCSD, San Diego. (January 2021–). NIH Program Office: National Institute of Diabetes and Digestive and Kidney Diseases, Division of Kidney, Urologic, and Hematologic Diseases, Bethesda, MD. NIH Project Scientist: Julia Barthold, MD.

Funding Information:
Fitzgerald: Royalties: UpToDate, Expert Witness. Fok: Royalties: UpToDate, Consultant: UroCure. Kenton: Expert Witness: Butler Snow/Ethicon, Grant Funding: Axonics. Lowder: Expert witness. Lukacz: Consultant: Axonics, Pathnostics; Scientific Advisor: Urovant; Grant funding: Boston Scientific, Uroplasty/Cogentix; Royalties: UpToDate. Markland: Federal grant funding, NIH, VA, AHRQ (see COI form). Meister: None. Smith: None. Wyman: None. Rudser: None. Newman: Consultant: EBT Medical, COSM, Urovant; Research Funding: Society for Urologic Nurses and Associates; Editorial: Digital Science Press; Royalties: Springer.

Publisher Copyright:
© 2022 Wiley Periodicals LLC.


  • bladder health
  • in-person examination
  • musculoskeletal assessment
  • pelvic health
  • pelvic muscle
  • physical function
  • women's health


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