The Response of Cancer Cell Populations to Therapies

Danika Lindsay; Colleen M. Garvey; Shannon M. Mumenthaler; Jasmine Y Foo

doi:10.1016/B978-0-12-804310-3.00010-7

The Response of Cancer Cell Populations to Therapies

Danika Lindsay, Colleen M. Garvey, Shannon M. Mumenthaler, Jasmine Y Foo

School of Mathematics

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Scopus citations

Abstract

In this chapter we discuss, from an evolutionary perspective, the response of cancer cell populations to therapeutic intervention. There are many factors that influence therapeutic response. Here we focus on examples of cell-intrinsic and -extrinsic mechanisms of current interest to the cancer biology and evolution communities: the roles of (1) phenotypic plasticity and (2) the tumor microenvironment.

Original language	English (US)
Title of host publication	Ecology and Evolution of Cancer
Publisher	Elsevier Inc.
Pages	137-152
Number of pages	16
ISBN (Electronic)	9780128043806
ISBN (Print)	9780128043103
DOIs	https://doi.org/10.1016/B978-0-12-804310-3.00010-7
State	Published - Feb 14 2017

Keywords

Cancer treatment response
Plasticity
Tumor microenvironment

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/B978-0-12-804310-3.00010-7

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title = "The Response of Cancer Cell Populations to Therapies",

abstract = "In this chapter we discuss, from an evolutionary perspective, the response of cancer cell populations to therapeutic intervention. There are many factors that influence therapeutic response. Here we focus on examples of cell-intrinsic and -extrinsic mechanisms of current interest to the cancer biology and evolution communities: the roles of (1) phenotypic plasticity and (2) the tumor microenvironment.",

keywords = "Cancer treatment response, Plasticity, Tumor microenvironment",

author = "Danika Lindsay and Garvey, {Colleen M.} and Mumenthaler, {Shannon M.} and Foo, {Jasmine Y}",

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AU - Garvey, Colleen M.

AU - Mumenthaler, Shannon M.

AU - Foo, Jasmine Y

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KW - Plasticity

KW - Tumor microenvironment

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M3 - Chapter

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BT - Ecology and Evolution of Cancer

PB - Elsevier Inc.

ER -

The Response of Cancer Cell Populations to Therapies

Abstract

Keywords

UN SDGs

Publisher link

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