The relative importance of monoamine oxidase and catechol-O-methyl transferase on the physiologic response to administered norepinephrine in the turkey

M E Elhalawani, P. E. Waibel

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

1. The pattern of monoamine oxidase (MAO) activity is comparable in rat, turkey and chicken tissues, with the liver having the highest activity, followed by the kidney and then the heart. 2. Catechol-O-methyl transferase (COMT) has no definite pattern of activity in the organs of the two avian species studied, and is markedly lower as compared to that of the rat. 3. Cardiac and hepatic MAO levels increase, whereas COMT activities remain low with advancing age in the turkey. 4. MAO but not COMT inhibition potentiates the cardio-vascular responses to administered norepinephrine in the turkey.

Original languageEnglish (US)
Pages (from-to)35-39
Number of pages5
JournalComparative Biochemistry and Physiology. Part C, Comparative
Volume52
Issue number1
DOIs
StatePublished - Oct 1 1975

Keywords

  • Avian
  • blood pressure
  • catechol-O-methyl transferase
  • monoamine oxidase
  • pyrogallol
  • tranylcypromine

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