Using self-discrepancy theory as a theoretical framework, this study examines the interactive effects of self-monitoring and type of self-guide (i.e., own vs. other standpoint) on the relationship between self-discrepancies and affective states. Over two sessions, 294 undergraduates completed the Self-Monitoring Scale, the Selves Questionnaire (either from the own or other standpoint), the Beck Depression Inventory, the Hopkins Symptom Checklist, and the Social Anxiety subscale of the Self-Consciousness Scale. For low self-monitors, depression and anxiety were predicted only by self-discrepancies from the own standpoint on the self. For high self-monitors, depression and anxiety were more strongly predicted by self-discrepancies from the other than the own standpoint on the self. The authors discuss the role of individual differences in understanding when self-discrepancies have implications for individuals' affective states.