The relationship between counseling and adherence to antiretroviral therapy among pregnant and breastfeeding women enrolled in option b+

Jerry John Nutor, Jaime C. Slaughter-Acey, Patience A. Afulani, Moses M. Obimbo, Sanyu A. Mojola

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

The aim of the study was to investigate the relationship between counseling prior to starting antiretroviral treatment (ART) and adherence to treatment among women enrolled in Option B+ in Zambia. Using convenience sampling, 150 HIV+ women enrolled in an Option B+ treatment regimen in rural and urban districts were recruited. Four generalized Poisson regression models were built to assess the association between counseling and adherence to ART. In all, 75% of the participants reported adherence in the past 7 days. In adjusted analyses, there was a significant positive relationship between counseling and adherence in the rural district (prevalence ratio [PR] 2.52, 95% CI [1.19, 5.35], n = 81) but not in the urban district (PR = 0.77, 95% CI [0.15, 3.91], n = 69). Offering counseling prior to initiating antiret-roviral treatment to HIV+ women is particularly important for promoting medication adherence in rural settings of low resourced countries.

Original languageEnglish (US)
Pages (from-to)378-391
Number of pages14
JournalAIDS Education and Prevention
Volume32
Issue number5
DOIs
StatePublished - Oct 2020

Bibliographical note

Funding Information:
Jerry John Nutor, PhD, RN, is affiliated with the Department of Family Health Care Nursing, School of Nursing, University of California, San Francisco, California. Jaime C. Slaughter-Acey, PhD, MPH, is affiliated with the Division of Epidemiology and Community Health, School of Public Health, University of Minnesota. Patience A. Afulani, MBChB, MPH, PhD, is an assistant professor in the Departments Epidemiology & Biostatistics and Obstetrics, Gynecology, & Reproductive Sciences, University of California, San Francisco. Moses M. Obimbo, MD, PhD, is affiliated with the Departments of Human Anatomy and Obstetrics and Gynecology, University of Nairobi, Nairobi, Kenya. Sanyu A. Mojola, PhD, is affiliated with the Department of Sociology, Woodrow Wilson School of Public and International Affairs, and Office of Population Research, Princeton University, Princeton, New Jersey. Research for this article was made possible by the Dornsife Global Development Scholar Program (Drexel University) and World Vision through a grant to the first author as part of his PhD dissertation project. The authors also wish to thank Dr. Julene K. Johnson, Associate Dean of Research, School of Nursing at University of California, San Francisco (UCSF) for editing the paper and also Dr. Thomas Hoffman, UCSF, for his statistical support. Address correspondence to Jerry John Nutor, PhD, RN, Department of Family Health Care Nursing, School of Nursing, University of California, San Francisco, 2 Koret Way, Ste. N431G, San Francisco, CA 94143. E-mail: Jerry.Nutor@ucsf.edu

Publisher Copyright:
© 2020 The Guilford Press.

Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.

Keywords

  • Adherence
  • Antiretrovirals
  • Counseling
  • HIV
  • Option B+
  • Zambia

PubMed: MeSH publication types

  • Journal Article
  • Research Support, Non-U.S. Gov't

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