The RDoC initiative and the structure of psychopathology

Research output: Contribution to journalArticlepeer-review

18 Scopus citations


The NIMH Research Domain Criteria (RDoC) project represents a welcome effort to circumvent the limitations of psychiatric categories as phenotypes for psychopathology research. Here, we describe the hierarchical and dimensional structure of phenotypic psychopathology and illustrate how this structure provides phenotypes suitable for RDoC research on neural correlates of psychopathology. A hierarchical and dimensional approach to psychopathology phenotypes holds great promise for delineating connections between neuroscience constructs and the patterns of affect, cognition, and behavior that constitute manifest psychopathology.

Original languageEnglish (US)
Pages (from-to)351-354
Number of pages4
Issue number3
StatePublished - Mar 1 2016


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