TY - JOUR
T1 - The Quebec Low Back Pain Study
T2 - A protocol for an innovative 2-tier provincial cohort
AU - Pagé, Gabrielle M.
AU - Lacasse, Anaïs
AU - Beaudet, Nicolas
AU - Choinière, Manon
AU - Deslauriers, Simon
AU - Diatchenko, Luda
AU - Dupuis, Laurent
AU - Grégoire, Stéphanie
AU - Hovey, Richard
AU - Leclair, Erwan
AU - Leonard, Guillaume
AU - Meloto, Carolina B.
AU - Montagna, Francesca
AU - Parent, Alexandre
AU - Rainville, Pierre
AU - Roy, Jean Sebastien
AU - Roy, Mathieu
AU - Ware, Mark A.
AU - Wideman, Timothy H.
AU - Stone, Laura S.
N1 - Publisher Copyright:
© 2019 The Author(s).
PY - 2020/1/1
Y1 - 2020/1/1
N2 - Introduction: The neurobiological mechanisms underlying recovery from or persistence of low back pain (LBP) remain misunderstood, limiting progress toward effective management. We have developed an innovative two-tier design to study the transition from acute to chronic LBP. The objective of the first tier is to create a provincial web-based infrastructure to recruit and monitor the trajectory of individuals with acute LBP. The objective of the second tier is to fuel hypothesis-driven satellite data collection centers with specialized expertise to study the role of biomechanical, epigenetic, genetic, neuroanatomical, ontological, physiological, psychological, and socioeconomic factors in LBP chronicity. Methods: This article describes the first tier of the protocol: Establishment of the Core Dataset and Cohort. Adults with acute LBP will be recruited through networks, media, and health care settings. A web-based interface will be used to collect self-reported variables at baseline and at 3, 6, 12, and 24months. Acute LBP will be defined according to the Dionne 2008 consensus. Measurements will include the Canadian minimum data set for chronic LBP research, DN4 for neuropathic pain, comorbidities, EQ-5D-5L for quality of life, and linkage with provincial medico-administrative databases. The primary outcome will be the transition to chronic LBP, as defined by Deyo 2014. Secondary outcomes include health care resource utilization, disability, sick leave, mood, and quality of life. Perspective: This study brings together diverse research expertise to investigate the transition from acute to chronic LBP, characterize the progression to recovery or chronicity, and identify patterns associated with that progression.
AB - Introduction: The neurobiological mechanisms underlying recovery from or persistence of low back pain (LBP) remain misunderstood, limiting progress toward effective management. We have developed an innovative two-tier design to study the transition from acute to chronic LBP. The objective of the first tier is to create a provincial web-based infrastructure to recruit and monitor the trajectory of individuals with acute LBP. The objective of the second tier is to fuel hypothesis-driven satellite data collection centers with specialized expertise to study the role of biomechanical, epigenetic, genetic, neuroanatomical, ontological, physiological, psychological, and socioeconomic factors in LBP chronicity. Methods: This article describes the first tier of the protocol: Establishment of the Core Dataset and Cohort. Adults with acute LBP will be recruited through networks, media, and health care settings. A web-based interface will be used to collect self-reported variables at baseline and at 3, 6, 12, and 24months. Acute LBP will be defined according to the Dionne 2008 consensus. Measurements will include the Canadian minimum data set for chronic LBP research, DN4 for neuropathic pain, comorbidities, EQ-5D-5L for quality of life, and linkage with provincial medico-administrative databases. The primary outcome will be the transition to chronic LBP, as defined by Deyo 2014. Secondary outcomes include health care resource utilization, disability, sick leave, mood, and quality of life. Perspective: This study brings together diverse research expertise to investigate the transition from acute to chronic LBP, characterize the progression to recovery or chronicity, and identify patterns associated with that progression.
KW - Acute
KW - Chronic
KW - Inception cohort
KW - Low back pain
KW - Persistence
KW - Two-stage sampling
UR - https://www.scopus.com/pages/publications/85101325597
UR - https://www.scopus.com/pages/publications/85101325597#tab=citedBy
U2 - 10.1097/PR9.0000000000000799
DO - 10.1097/PR9.0000000000000799
M3 - Article
AN - SCOPUS:85101325597
SN - 2471-2531
VL - 5
SP - E799
JO - Pain Reports
JF - Pain Reports
IS - 1
ER -