The Predictive Value of Microalbuminuria

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An elevated urinary albumin excretion (termed microalbuminuria) has been proposed as a predictor for later development of clinical diabetic nephropathy (hypertension, falling glomerular filtration rate [GFR], and urinary albumin excretion > 300 mg/24 h). However, review of the original reports on the predictability of microalbuminuria revealed a concomitant presence of elevated BP and a propensity to falling GFR. Thus, the predictability of microalbuminuria rests on the added evaluation of BP and GFR. Additional investigation is needed to address the possibility that microalbuminuria and either a rising BP or a falling GFR or both indicates established diabetic nephropathy rather than predicting its development.

Original languageEnglish (US)
Pages (from-to)25-28
Number of pages4
JournalAmerican Journal of Kidney Diseases
Issue number1
StatePublished - Jan 1 1989


  • Diabetes
  • albuminuria
  • nephropathy


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