The Plant Genome: Decoding the Transcriptional Hardwiring

Erich Grotewold, Nathan Springer

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Scopus citations

Abstract

Transcription consists of the retrieval of information stored in the genome into mRNAs by DNA-dependent RNA polymerases (RNAPs). The regulation of transcription is controlled through cis-regulatory elements (CREs) that tether regulatory proteins, such as transcription factors (TFs), which act to direct the RNAP to transcribe specific genes with particular temporal and spatial patterns. Here, we provide a plant gene-centred perspective of how the regulatory code is believed to be hardwired and how TFs interpret this code to deliver the appropriate signals to the transcriptional machinery.

Original languageEnglish (US)
Title of host publicationPlant Systems Biology
PublisherBlackwell Publishing Ltd
Pages196-228
Number of pages33
Volume35
ISBN (Electronic)9781444312249
ISBN (Print)9781405162838
DOIs
StatePublished - Aug 18 2009

Keywords

  • Chromatin
  • Promoter
  • Regulatory motif
  • TATA
  • Transcription factor
  • cis-regulatory element

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  • Cite this

    Grotewold, E., & Springer, N. (2009). The Plant Genome: Decoding the Transcriptional Hardwiring. In Plant Systems Biology (Vol. 35, pp. 196-228). Blackwell Publishing Ltd. https://doi.org/10.1002/9781444312249.ch6