The pathology of cardiomyopathies

Zeev Vlodaver, James H. Moller, Shannon M. Mackey-Bojack, K P Madhu

Research output: Chapter in Book/Report/Conference proceedingChapter


Understanding the various types of cardiomyopathies is important for identifying individual patients' conditions and developing appropriate treatment plans. Yet defining and categorizing "cardiomyopathies" has proved no simple task-starting in 1972 when Goodwin and Oakley defined them as myocardial diseases of unknown origin and proposed three types. In 1990, the World Health Organization and International Society and Federation of Cardiology expanded the definition to diseases of myocardium with myocardial dysfunction. This chapter adapts the American Heart Association's genetic-based classification introduced in 2006. Within primary cardiomyopathy, we use genetic, nongenetic, and "acquired" disease categories-describing presenting symptoms and the use of imaging, biopsies, and the role of family histories, in some cases, for making a diagno sis.

Original languageEnglish (US)
Title of host publicationCongestive Heart Failure and Cardiac Transplantation
Subtitle of host publicationClinical, Pathology, Imaging and Molecular Profiles
PublisherSpringer International Publishing
Number of pages12
ISBN (Electronic)9783319445779
ISBN (Print)9783319445755
StatePublished - Jun 1 2017


  • Cardiomyopathy
  • Dilated cardiomyopathy
  • Hypertrophic cardiomyopathy
  • Myocardial disease
  • Obliterative cardiomyopathy
  • Restrictive cardiomyopathy


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