Abstract
We have identified a 56-kb pathogenicity island (PAI) in avian pathogenic Escherichia coli strain O1:K1 (APEC-O1). This PAI, termed PAI I APEC-o1 is integrated adjacent to the 3′ end of the pheV tRNA gene. It carries putative virulence genes of APEC (pap operon), other E. coli genes (tia and ireA), and a 1.5-kb region unique to APEC-O1. The kps gene cluster required for the biosynthesis of polysialic acid capsule was mapped to a location immediately downstream of this PAI.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 744-749 |
| Number of pages | 6 |
| Journal | Infection and immunity |
| Volume | 74 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 2006 |
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