The pap operon of avian pathogenic Escherichia coli strain O1:K1 is located on a novel pathogenicity island

Subhashinie Kariyawasam, Timothy J. Johnson, Lisa K. Nolan

Research output: Contribution to journalArticlepeer-review

35 Scopus citations

Abstract

We have identified a 56-kb pathogenicity island (PAI) in avian pathogenic Escherichia coli strain O1:K1 (APEC-O1). This PAI, termed PAI I APEC-o1 is integrated adjacent to the 3′ end of the pheV tRNA gene. It carries putative virulence genes of APEC (pap operon), other E. coli genes (tia and ireA), and a 1.5-kb region unique to APEC-O1. The kps gene cluster required for the biosynthesis of polysialic acid capsule was mapped to a location immediately downstream of this PAI.

Original languageEnglish (US)
Pages (from-to)744-749
Number of pages6
JournalInfection and immunity
Volume74
Issue number1
DOIs
StatePublished - Jan 2006

Fingerprint Dive into the research topics of 'The pap operon of avian pathogenic Escherichia coli strain O1:K1 is located on a novel pathogenicity island'. Together they form a unique fingerprint.

Cite this