The Neuroscience of Pain: Biobehavioral, Developmental, and Psychosocial Mechanisms Relevant to Intervention Targets

Lauren Y. Atlas, Mustafa N al'Absi

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations

Abstract

Chronic pain is a major problem in clinical medicine and public health, affecting approximately one in five adults, and is associated with significant societal and familial burden. Early-life adversities, psychological, and biobehavioral factors are associated with an elevated risk of the subsequent development of chronic pain. In this special issue of Psychosomatic Medicine, articles address the neuroscientific, psychological, and biobehavioral processes involved in acute and chronic pain. We focus on the following themes that emerged in this special issue: (a) risk factors and early adversity as related to chronic pain; (b) the role of expectations in shaping pain perception; and (c) mechanisms of interventions targeting pain modulation. This article concludes by outlining important new targets for research, including the neurobiology of pain, important methodological challenges, and targets for personalized pain interventions.

Original languageEnglish (US)
Pages (from-to)788-790
Number of pages3
JournalPsychosomatic medicine
Volume80
Issue number9
DOIs
StatePublished - Nov 1 2018

Bibliographical note

Publisher Copyright:
Copyright © 2018 by the American Psychosomatic Society

Keywords

  • Adversity
  • Development
  • Expectations
  • Intervention
  • Neuroscience
  • Pain

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