@article{6b541a95df12444aa073bb41c95ea962,
title = "The NEIGHBOR Consortium Primary Open-Angle glaucoma genome-wide association study: Rationale, study design, and clinical variables",
abstract = "Primary open-angle glaucoma (POAG) is a common disease with complex inheritance. The identification of genes predisposing to POAG is an important step toward the development of novel gene-based methods of diagnosis and treatment. Genome-wide association studies (GWAS) have successfully identified genes contributing to complex traits such as POAG however, such studies frequently require very large sample sizes, and thus, collaborations and consortia have been of critical importance for the GWAS approach. In this report we describe the formation of the NEIGHBOR consortium, the harmonized case control definitions used for a POAG GWAS, the clinical features of the cases and controls, and the rationale for the GWAS study design.",
keywords = "Genetics, Genome-wide association study, Primary open-angle glaucoma",
author = "Wiggs, {Janey L.} and Hauser, {Michael A.} and Wael Abdrabou and Allingham, {Robert Rand} and Budenz, {Donald L.} and Elizabeth Delbono and Friedman, {David S.} and Kang, {Jae H.} and Douglas Gaasterland and Terry Gaasterland and Lee, {Richard K.} and Lichter, {Paul R.} and Stephanie Loomis and Yutao Liu and Cathy Mccarty and Medeiros, {Felipe A.} and Moroi, {Sayoko E.} and Olson, {Lana M.} and Anthony Realini and Richards, {Julia E.} and Rozsa, {Frank W.} and Schuman, {Joel S.} and Kuldev Singh and Stein, {Joshua D.} and Douglas Vollrath and Weinreb, {Robert N.} and Gadi Wollstein and Yaspan, {Brian L.} and Sachiko Yoneyama and Don Zack and Kang Zhang and Margaret Pericak-Vance and Pasquale, {Louis R.} and Haines, {Jonathan L.}",
year = "2013",
month = sep,
doi = "10.1097/IJG.0b013e31824d4fd8",
language = "English (US)",
volume = "22",
pages = "517--525",
journal = "Journal of Glaucoma",
issn = "1057-0829",
publisher = "Lippincott Williams and Wilkins Ltd.",
number = "7",
}