In an attempt to study the natural history of isolated pulmonary valvular stenosis, 21 children with serial cardiac catheterizations were reviewed. The clinical, electrocardiographic, and roentgenographic features in the majority of these cases did not suggest that there had been a change in the severity of the pulmonary stenosis during the interval of study. In 19 of the 21 cases the right ventricular systolic pressure remained in the same range over the period of observation. Of the 17 cases in which complete data were available, 16 exhibited an increase in the pulmonary valve area, which was in proportion to the increase in body growth. It is concluded that the increasing severity of pulmonary valvular stenosis that has been reported is due not to a failure of the pulmonary valve orifice to increase in size as the child grows, but rather possibly to factors of infundibular hypertrophy or myocardial fibrosis.
Bibliographical noteFunding Information:
* From the Department of Pedlatrlcs, Umverslty of Mmnesota, Mmneapohs, Mmn This study was supported m part by Pubhc Health Service Fellowship HE 19,867, National Heart Imtltute Bethesda, Md
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