The natural history of human immunodeficiency virus infection

Alan R. Lifson, George W. Rutherford, Harold W. Jaffe, Alan R. Lifson

Research output: Contribution to journalArticlepeer-review

150 Scopus citations


NOTE FROM DR. MERLE A. SANDE -What happens after an individual is infected with human immunodeficiency virus (HIV)? In how many infected individuals will infection actually progress to clinical disease? How long does this take, and how can the clinician tell that progression from asymptomatic infection to symptomatic disease is beginning? What, if anything, can be done to slow progression? These are some of the most pressing questions with which infectious diseases clinicians are faced today. Drs. George W. Ruther-ford and Alan R. Lifson of the San Francisco Department of Public Health and Dr. Harold W. Jaffe of the Centers for Disease Control have been major contributors in shedding light on these crucial questions. This AIDS Commentary comprises their collective, current thoughts on the progression of HIV infection.

Original languageEnglish (US)
Pages (from-to)1360-1367
Number of pages8
JournalJournal of Infectious Diseases
Issue number6
StatePublished - Dec 1988


Dive into the research topics of 'The natural history of human immunodeficiency virus infection'. Together they form a unique fingerprint.

Cite this