The mycobiome: Impact on health and disease states

Najla El-Jurdi, Mahmoud A. Ghannoum

Research output: Contribution to journalArticlepeer-review

20 Scopus citations


The term "microbiome" refers to microorganisms (microbiota) and their genomes (metagenome) coexisting with their hosts. Some researchers coined the term "second genome" to underscore the importance of the microbiota and its collective metagenome on their host's health and/or disease. It is now undeniable that the commensal fungal microorganisms, alongside the other components of the microbiota, play a central role in association with the human host. In recognition, projects were launched nationally and internationally to unify efforts to characterize the microbiome and elucidate the functional role of the microbiota and the mechanism(s) by which these organisms and their metabolites (metabolome) may affect health and disease states. In this article, we will highlight the role of the fungal community as an indispensable component of the microbiome.

Original languageEnglish (US)
Article numberFUNK-0045-2016
JournalMicrobiology Spectrum
Issue number3
StatePublished - Jun 1 2017
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2017 American Society for Microbiology. All rights reserved.


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