TY - JOUR
T1 - The mycobiome
T2 - Impact on health and disease states
AU - El-Jurdi, Najla
AU - Ghannoum, Mahmoud A.
N1 - Publisher Copyright:
© 2017 American Society for Microbiology. All rights reserved.
PY - 2017/6/1
Y1 - 2017/6/1
N2 - The term "microbiome" refers to microorganisms (microbiota) and their genomes (metagenome) coexisting with their hosts. Some researchers coined the term "second genome" to underscore the importance of the microbiota and its collective metagenome on their host's health and/or disease. It is now undeniable that the commensal fungal microorganisms, alongside the other components of the microbiota, play a central role in association with the human host. In recognition, projects were launched nationally and internationally to unify efforts to characterize the microbiome and elucidate the functional role of the microbiota and the mechanism(s) by which these organisms and their metabolites (metabolome) may affect health and disease states. In this article, we will highlight the role of the fungal community as an indispensable component of the microbiome.
AB - The term "microbiome" refers to microorganisms (microbiota) and their genomes (metagenome) coexisting with their hosts. Some researchers coined the term "second genome" to underscore the importance of the microbiota and its collective metagenome on their host's health and/or disease. It is now undeniable that the commensal fungal microorganisms, alongside the other components of the microbiota, play a central role in association with the human host. In recognition, projects were launched nationally and internationally to unify efforts to characterize the microbiome and elucidate the functional role of the microbiota and the mechanism(s) by which these organisms and their metabolites (metabolome) may affect health and disease states. In this article, we will highlight the role of the fungal community as an indispensable component of the microbiome.
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U2 - 10.1128/microbiolspec.FUNK-0045-2016
DO - 10.1128/microbiolspec.FUNK-0045-2016
M3 - Article
C2 - 28597821
AN - SCOPUS:85020299442
SN - 2165-0497
VL - 5
JO - Microbiology Spectrum
JF - Microbiology Spectrum
IS - 3
M1 - FUNK-0045-2016
ER -