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The mTOR pathway is activated in glial cells in mesial temporal sclerosis
Alexander A. Sosunov
, Xiaoping Wu
,
Robert A. McGovern
, David G. Coughlin
, Charles B. Mikell
, Robert R. Goodman
, Guy M. McKhann
Research output
:
Contribution to journal
›
Article
›
peer-review
62
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Scopus citations
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Keyphrases
Glial Cells
100%
Mammalian Target of Rapamycin (mTOR)
100%
Temporal Lobe
100%
Mammalian Target of Rapamycin Pathway
100%
Temporal Lobe Epilepsy
77%
Sclerotic
55%
Phospho-S6
55%
Epilepsy
33%
Hippocampus
33%
Microglia
22%
Tuberous Sclerosis Complex
22%
Astrocytes
22%
Astrogliosis
22%
Astroglial Scar
22%
Pilocarpine Model
22%
Human Neocortex
22%
Tuber
11%
Protein Kinase
11%
Magnetic Resonance Imaging
11%
Scar
11%
Pathologic
11%
Neocortex
11%
Neuronal Loss
11%
Human Tissue
11%
Cellular Changes
11%
Cellular Processes
11%
Normal Human
11%
Medical Therapy
11%
Cortical Astrocytes
11%
Neocortical
11%
Scar Tissue
11%
Confocal Microscopy
11%
Immunoreactivity
11%
Immunostaining
11%
Brain Malformation
11%
Immunopositivity
11%
Human Hippocampus
11%
Developmental Brain
11%
Astroglial Cells
11%
Immunohistochemical Investigation
11%
Pilocarpine-induced Epilepsy
11%
Preserved Areas
11%
Cortical Tuber
11%
Epileptic Hippocampus
11%
Cellular Alterations
11%
Neuroscience
Mammalian Target of Rapamycin
100%
Microglia
100%
Hippocampal Sclerosis
100%
Mesial Temporal Lobe Epilepsy
70%
Hippocampus
50%
Pilocarpine
30%
Astrocyte
30%
Astrogliosis
20%
Tuberous Sclerosis
20%
Protein Kinases
10%
Magnetic Resonance Imaging
10%
Confocal Microscopy
10%
Cortical Malformation
10%
Immunohistochemistry
10%