TY - JOUR
T1 - The molecular genetic basis of herbivory between butterflies and their host plants
AU - Nallu, Sumitha
AU - Hill, Jason A.
AU - Don, Kristine
AU - Sahagun, Carlos
AU - Zhang, Wei
AU - Meslin, Camille
AU - Snell-Rood, Emilie
AU - Clark, Nathan L.
AU - Morehouse, Nathan I.
AU - Bergelson, Joy
AU - Wheat, Christopher W.
AU - Kronforst, Marcus R.
N1 - Publisher Copyright:
© 2018, The Author(s).
PY - 2018/9/1
Y1 - 2018/9/1
N2 - Interactions between herbivorous insects and their host plants are a central component of terrestrial food webs and a critical topic in agriculture, where a substantial fraction of potential crop yield is lost annually to pests. Important insights into plant–insect interactions have come from research on specific plant defences and insect detoxification mechanisms. Yet, much remains unknown about the molecular mechanisms that mediate plant–insect interactions. Here we use multiple genome-wide approaches to map the molecular basis of herbivory from both plant and insect perspectives, focusing on butterflies and their larval host plants. Parallel genome-wide association studies in the cabbage white butterfly, Pieris rapae, and its host plant, Arabidopsis thaliana, pinpointed a small number of butterfly and plant genes that influenced herbivory. These genes, along with much of the genome, were regulated in a dynamic way over the time course of the feeding interaction. Comparative analyses, including diverse butterfly/plant systems, showed a variety of genome-wide responses to herbivory, as well as a core set of highly conserved genes in butterflies as well as their host plants. These results greatly expand our understanding of the genomic causes and evolutionary consequences of ecological interactions across two of nature’s most diverse taxa, butterflies and flowering plants.
AB - Interactions between herbivorous insects and their host plants are a central component of terrestrial food webs and a critical topic in agriculture, where a substantial fraction of potential crop yield is lost annually to pests. Important insights into plant–insect interactions have come from research on specific plant defences and insect detoxification mechanisms. Yet, much remains unknown about the molecular mechanisms that mediate plant–insect interactions. Here we use multiple genome-wide approaches to map the molecular basis of herbivory from both plant and insect perspectives, focusing on butterflies and their larval host plants. Parallel genome-wide association studies in the cabbage white butterfly, Pieris rapae, and its host plant, Arabidopsis thaliana, pinpointed a small number of butterfly and plant genes that influenced herbivory. These genes, along with much of the genome, were regulated in a dynamic way over the time course of the feeding interaction. Comparative analyses, including diverse butterfly/plant systems, showed a variety of genome-wide responses to herbivory, as well as a core set of highly conserved genes in butterflies as well as their host plants. These results greatly expand our understanding of the genomic causes and evolutionary consequences of ecological interactions across two of nature’s most diverse taxa, butterflies and flowering plants.
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U2 - 10.1038/s41559-018-0629-9
DO - 10.1038/s41559-018-0629-9
M3 - Article
C2 - 30076351
AN - SCOPUS:85052076293
SN - 2397-334X
VL - 2
SP - 1418
EP - 1427
JO - Nature Ecology and Evolution
JF - Nature Ecology and Evolution
IS - 9
ER -