The Modern Approach to the Diagnosis of Occupational Disease

Raymond D. Harbison, Jeffrey H. Mandel

Research output: Chapter in Book/Report/Conference proceedingChapter


An understanding of the health effects that may occur from occupational exposures is critical in terms of the potential human toll and an industry's success and sustainability. In the context of modern medicine, the diagnosis of an occupational disease is a multidisciplinary process and includes input from professionals in occupational medicine, nursing, industrial hygiene, toxicology, epidemiology, engineering, and others. Risk assessment is the process of determining whether a chemical will produce harm under specified conditions of exposure. The issue of whether a particular chemical exposure causes disease in humans may be approached in different ways. Permissible exposure limit (PEL), recommended exposure limit (REL), and threshold limit value (TLV) are occupational exposure limits developed by OSHA, the U. S. National Institute for Occupational Safety and Health (NIOSH), or the American Conference of Governmental Industrial Hygienists (ACGIH), respectively.

Original languageEnglish (US)
Title of host publicationHamilton and Hardy's Industrial Toxicology
Subtitle of host publicationSixth Edition
Number of pages12
ISBN (Electronic)9781118834015
ISBN (Print)9780470929735
StatePublished - Mar 20 2015

Bibliographical note

Publisher Copyright:
© 2015 by John Wiley & Sons, Inc. All rights reserved.


  • Epidemiology
  • Occupational disease
  • Permissible exposure limit (PEL)
  • Risk assessment
  • Toxicology
  • recommended exposure limit (REL)
  • threshold limit value (TLV)


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