The moderating role of depression in the association between hypertension during pregnancy and birth outcomes

Yueqi Li, Jen Jen Chang, Ruikun Zuo, Hong Xian, Darcell Scharff

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: Investigate how hypertension during pregnancy (HDP) and depression during pregnancy (DDP) independently and jointly affect infant birth outcomes. Methods: This population-based, retrospective cohort study included a sample of 68,052 women who participated in PRAMS 2016–2018 survey. Poisson regression was used for adjusted relative risks (aRRs). Results: Compared to women without HDP and DDP, aRRs for PTB and LBW among women with both HDP and DDP are 2.04 (95% CI 1.73, 2.42) and 2.84 (95% CI 2.27, 3.56), respectively, albeit lower than the expected joint effect of risk. Conclusion: DDP may modify the association between HDP and PTB, LBW.

Original languageEnglish (US)
Article number2226703
JournalHypertension in Pregnancy
Volume42
Issue number1
DOIs
StatePublished - 2023
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2023 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

Keywords

  • depression
  • Hypertension
  • low birth weight
  • pregnancy
  • preterm birth

PubMed: MeSH publication types

  • Journal Article

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