Abstract
1H{13C} n.m.r. difference spectroscopy has been used to determine the intact incorporation of [methyl-13CD 3]methionine into the C-1- and C-12α-methyl groups of vitamin B12.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 544-546 |
| Number of pages | 3 |
| Journal | Journal of the Chemical Society, Chemical Communications |
| Issue number | 14 |
| DOIs | |
| State | Published - 1976 |
Bibliographical note
Funding Information:COMM., 1976 methyl groups and the proton mobility at C-18 and C-19, as well as the nature of the liberated C-20 carbon. Using different techniques, Professors Arigoni and Battersby have reached identical conclusions regarding the intact nature of C-1 methyl group in corrin biosynthesis as described in the accompanying communications.* We thank the National Institutes of Health and the National Science Foundation for generous support of this research, Dr. J. H. Prestegard for helpful discussions, and Mr. Arnold Brown for cultivating P. sherrnanii. (Received, 21st Afivil 1976; Corn. 447.) -f This value for 3J(C-H) was obtained by computer simulation 1 A. I. Scott, Tetrahedron, 1975, 31, 2639; see also A. R. Battersby, M. Ihara, E. McDonald, F.