The mechanism of force generation in myosin: A disorder-to-order transition, coupled to internal structural changes

Keyphrases

• Myosin 100%
• Order-disorder Transition 100%
• Force Generation 100%
• Myosin Head 100%
• Internal Structural Changes 100%
• Actin 60%
• Electron Paramagnetic Resonance 60%
• Catalytic Domain 60%
• Regulatory Light Chain 60%
• Myofibril 60%
• Time-resolved Fluorescence 40%
• Anisotropy 40%
• Ligand-binding Domain 40%
• Light Chain 40%
• ATPase Cycle 40%
• Molecular Mechanism 20%
• Muscle Fiber 20%
• Calcium Regulation 20%
• Spectroscopic Probe 20%
• Time-resolved 20%
• Bound States 20%
• Conformational Transition 20%
• Spin Label 20%
• Rotational Dynamics 20%
• Rotational Motion 20%
• Internal Dynamics 20%
• Stereospecific 20%
• Large Amplitude 20%
• Intermediate State 20%
• Nucleoside Analogues 20%
• Actin Binding 20%
• Weak Binding 20%
• Dynamic Disorder 20%
• Classical Model 20%
• Large-scale Dynamics 20%
• Distinct Angles 20%
• Internal Structure Changes 20%
• Rotational Disorder 20%
• Stronger Binding 20%
• Highly Ordered 20%

Biochemistry, Genetics and Molecular Biology

• Myosin Head 100%
• Light Chain 100%
• Actin 80%
• Enzyme Active Site 60%
• Myofibril 60%
• Dynamics 40%
• Electron Paramagnetic Resonance 40%
• Anisotropy 40%
• Binding Domain 40%
• Leporidae 40%
• ATPase 40%
• Conformation 20%
• Motion 20%
• Conformational Change 20%
• Time-Resolved Electron Paramagnetic Resonance 20%
• Spin Label 20%
• Scallop 20%