The laboratory mouse

Mice have been domesticated by humans for centuries, even millennia, and have been used in research since the 1600’s. However, development of the laboratory mouse as a research model accelerated with genetic experiments in the early 1900’s. Today, the laboratory mouse is recognized as the pre-eminent model for modern genetic research. In fact, over the last decade or so, most biomedical research facilities have experienced increases of up to three hundred percent in their mouse populations. Numerous other disciplines, including immunology, cancer biology, toxicology, developmental biology, aging research, and cardiovascular biology have recognized the mouse as a valuable research model. The Laboratory Mouse provides a single source reference for investigators, technicians, and animal caretakers charged with the care and/or use of mice in biomedical research. The book is particularly valuable to researchers at small institutions and to those who work at facilities that lack large, well-organized animal resource units.