The journey to autism: Insights from neuroimaging studies of infants and toddlers

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Abstract

By definition, autism spectrum disorder (ASD) is a neurodevelopmental disorder that emerges during early childhood. It is during this time that infants and toddlers transition from appearing typical across multiple domains to exhibiting the behavioral phenotype of ASD. Neuroimaging studies focused on this period of development have provided crucial knowledge pertaining to this process, including possible mechanisms underlying pathogenesis of the disorder and offering the possibility of prodromal or presymptomatic prediction of risk. In this paper, we review findings from structural and functional brain imaging studies of ASD focused on the first years of life and discuss implications for next steps in research and clinical applications.

Original languageEnglish (US)
Pages (from-to)479-495
Number of pages17
JournalDevelopment and psychopathology
Volume30
Issue number2
DOIs
StatePublished - May 1 2018

Bibliographical note

Publisher Copyright:
© 2017 Cambridge University Press.

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