TY - JOUR
T1 - The influence of age, sex, race, and body habitus on kidney weight in humans
AU - Kasiske, B. L.
AU - Umen, A. J.
PY - 1986
Y1 - 1986
N2 - The impact of age, sex, race, and body build on kidney weight was examined in 357 normal individuals who died suddenly. Multivariate, stepwise linear-regression analysis demonstrated that kidney weight was best predicted by body surface area. Age, sex, and race had no additional impact on kidney weight once differences in body build were taken into account. Similar results were obtained with heart and liver weights. These findings were confirmed using a second, independent paired sample of 16 lean and 16 massively obese adults. Body build-associated changes in kidney weight were paralleled by changes in both glomerular and tubulointerstitial areas. Body build is the major determinant of kidney weight and nephron size in normal humans.
AB - The impact of age, sex, race, and body build on kidney weight was examined in 357 normal individuals who died suddenly. Multivariate, stepwise linear-regression analysis demonstrated that kidney weight was best predicted by body surface area. Age, sex, and race had no additional impact on kidney weight once differences in body build were taken into account. Similar results were obtained with heart and liver weights. These findings were confirmed using a second, independent paired sample of 16 lean and 16 massively obese adults. Body build-associated changes in kidney weight were paralleled by changes in both glomerular and tubulointerstitial areas. Body build is the major determinant of kidney weight and nephron size in normal humans.
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M3 - Article
C2 - 3753571
AN - SCOPUS:0022545216
SN - 0003-9985
VL - 110
SP - 55
EP - 60
JO - Archives of Pathology and Laboratory Medicine
JF - Archives of Pathology and Laboratory Medicine
IS - 1
ER -