The impact of the coronavirus (COVID-19) pandemic on individuals with gastrointestinal disorders: A protocol of an international collaborative study

Nuno Ferreira, Antonina Mikocka-Walus, Miranda A.L. van Tilburg, Lesley A. Graff, Pragalathan Apputhurai, Manuel Barreiro de Acosta, Floor Bennebroek Evertsz, Johan Burisch, Bobby Lo, Megan Petrik, Inês A. Trindade, Sharon Jedel, Gabriele Moser, Anna Mokrowiecka, Charles N. Bernstein, Dan Dumitrascu, Alexander C. Ford, Andreas Stengel, Richard Gearry, Simon R. Knowles

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Objective: The COVID-19 pandemic has had a significant impact on mental health across the globe. People living with a chronic gastrointestinal (GI) disorder might be particularly at risk of mental health complications given higher rates of comorbid anxiety and depression compared to the healthy population. As GI disorders affect up to 40% of the population worldwide, this international collaborative study seeks to evaluate the extent of the impact of the COVID-19 pandemic on GI symptoms specifically and more generally on the well-being of those living with chronic GI conditions. Methods: A longitudinal survey with three time points (baseline, 6-month, and 12-month) will be conducted online. Adult participants with GI disorders from multiple countries will be recruited via patient associations, social media advertising, utilizing snowball sampling. Participants will be invited to complete a battery of questionnaires including demographic and health parameters, and measures of gastrointestinal symptoms, fear of COVID-19, perceived impact of COVID-19, illness perceptions, coping, depression, anxiety, stress, catastrophizing, and quality of life, using validated measures where available. Statistical analyses will include univariate descriptive models, multivariate models utilizing regression, mediation, and moderation, and latent growth models. Conclusions: This project may present novel information to the field of psychogastroenterology and may provide crucial information regarding the areas of impact for individuals with GI disorders during and following the pandemic. Further, this information can guide healthcare providers and patient associations on how to target support related to the pandemic mental health sequelae for these patients.

Original languageEnglish (US)
Article number110561
JournalJournal of Psychosomatic Research
StatePublished - Sep 1 2021

Bibliographical note

Publisher Copyright:
© 2021 Elsevier Inc.


  • Anxiety
  • COVID-19
  • Depression
  • Gastrointestinal disorders
  • Mental health
  • Quality of life
  • Stress


Dive into the research topics of 'The impact of the coronavirus (COVID-19) pandemic on individuals with gastrointestinal disorders: A protocol of an international collaborative study'. Together they form a unique fingerprint.

Cite this