The Impact of Bariatric Surgery on Breast Cancer Recurrence: Case Series and Review of Literature

Shijia Zhang, Sayeed Ikramuddin, Heather C. Beckwith, Adam C. Sheka, Keith M. Wirth, Anne H. Blaes

Research output: Contribution to journalArticlepeer-review

20 Scopus citations


Background: Excess body weight has been associated with worsening breast cancer survival. While bariatric surgery has been associated with less incident of breast cancer, the role that bariatric surgery plays after breast cancer diagnosis in terms of both feasibility and in preventing breast cancer recurrence is unclear. Methods: We report the outcomes of 13 individuals who underwent bariatric surgery after definitive breast cancer treatment at a single institution. Results: Thirteen females diagnosed with breast cancer (69.2% stage I, 23.1% stage II) at a median age of 42 years received bariatric surgery between 2001 and 2017. The median age of bariatric surgery was 52 years. Of the 13 patients, 46.2% underwent laparoscopic Roux-en-Y gastric bypass and 38.5% laparoscopic sleeve gastrectomy. The median time from breast cancer treatment to bariatric surgery was 3 years. The procedures were well tolerated. One female developed an abdominal wall hematoma. The average weight loss after 1 year and 2 years was 28.1% and 28.2%, respectively. There was a single breast cancer recurrence with a median follow-up of 11.7 years after breast cancer diagnosis and 5.3 years after bariatric surgery. Conclusions: Bariatric surgery after breast cancer treatment is feasible and well tolerated. Prospective trials evaluating bariatric surgery in obese breast cancer survivors should be considered.

Original languageEnglish (US)
Pages (from-to)780-785
Number of pages6
JournalObesity Surgery
Issue number2
StatePublished - Feb 1 2020

Bibliographical note

Funding Information:
Authors Shijia Zhang, Heather C. Beckwith, Adam C. Sheka, Keith M. Wirth, and Anne H. Blaes have nothing to disclose. Author Sayeed Ikramuddin received support from Medtronic for equipment for research studies, and Reshape Lifesciences for the grant support for clinical trials.

Publisher Copyright:
© 2019, The Author(s).


  • Bariatric surgery
  • Breast cancer
  • Recurrence
  • Weight loss


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