The Human Connectome Project: A data acquisition perspective

D. C. Van Essen; K. Ugurbil; E. Auerbach; D. Barch; T. E.J. Behrens; R. Bucholz; A. Chang; L. Chen; M. Corbetta; S. W. Curtiss; S. Della Penna; D. Feinberg; M. F. Glasser; N. Harel; A. C. Heath; L. Larson-Prior; D. Marcus; G. Michalareas; S. Moeller; R. Oostenveld; S. E. Petersen; F. Prior; B. L. Schlaggar; S. M. Smith; A. Z. Snyder; J. Xu; E. Yacoub

doi:10.1016/j.neuroimage.2012.02.018

The Human Connectome Project: A data acquisition perspective

D. C. Van Essen, K. Ugurbil, E. Auerbach, D. Barch, T. E.J. Behrens, R. Bucholz, A. Chang, L. Chen, M. Corbetta, S. W. Curtiss, S. Della Penna, D. Feinberg, M. F. Glasser, N. Harel, A. C. Heath, L. Larson-Prior, D. Marcus, G. Michalareas, S. Moeller, R. OostenveldS. E. Petersen, F. Prior, B. L. Schlaggar, S. M. Smith, A. Z. Snyder, J. Xu, E. Yacoub

Radiology

Research output: Contribution to journal › Review article › peer-review

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Abstract

The Human Connectome Project (HCP) is an ambitious 5-year effort to characterize brain connectivity and function and their variability in healthy adults. This review summarizes the data acquisition plans being implemented by a consortium of HCP investigators who will study a population of 1200 subjects (twins and their non-twin siblings) using multiple imaging modalities along with extensive behavioral and genetic data. The imaging modalities will include diffusion imaging (dMRI), resting-state fMRI (R-fMRI), task-evoked fMRI (T-fMRI), T1- and T2-weighted MRI for structural and myelin mapping, plus combined magnetoencephalography and electroencephalography (MEG/EEG). Given the importance of obtaining the best possible data quality, we discuss the efforts underway during the first two years of the grant (Phase I) to refine and optimize many aspects of HCP data acquisition, including a new 7T scanner, a customized 3T scanner, and improved MR pulse sequences.

Original language	English (US)
Pages (from-to)	2222-2231
Number of pages	10
Journal	NeuroImage
Volume	62
Issue number	4
DOIs	https://doi.org/10.1016/j.neuroimage.2012.02.018
State	Published - Oct 1 2012

Bibliographical note

Funding Information:
We thank the entire WU-Minn HCP consortium team for their excellent efforts that have contributed directly or indirectly to the plans described in this manuscript. Funded in part by the Human Connectome Project ( 1U54MH091657 ) from the 16 NIH Institutes and Centers that Support the NIH Blueprint for Neuroscience Research, and by the McDonnell Center for Systems Neuroscience at Washington University . Members of the WU-Minn HCP Consortium are listed at http://www.humanconnectome.org/about/hcp-investigators.html and http://www.humanconnectome.org/about/hcp-colleagues.html .

Keywords

Behavior
Connectivity
Diffusion imaging
FMRI
MEG/EEG
Twins

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10.1016/j.neuroimage.2012.02.018

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Van Essen, D. C., Ugurbil, K., Auerbach, E., Barch, D., Behrens, T. E. J., Bucholz, R., Chang, A., Chen, L., Corbetta, M., Curtiss, S. W., Della Penna, S., Feinberg, D., Glasser, M. F., Harel, N., Heath, A. C., Larson-Prior, L., Marcus, D., Michalareas, G., Moeller, S., ... Yacoub, E. (2012). The Human Connectome Project: A data acquisition perspective. NeuroImage, 62(4), 2222-2231. https://doi.org/10.1016/j.neuroimage.2012.02.018

Van Essen, DC, Ugurbil, K , Auerbach, E, Barch, D, Behrens, TEJ, Bucholz, R, Chang, A, Chen, L, Corbetta, M, Curtiss, SW, Della Penna, S, Feinberg, D, Glasser, MF, Harel, N, Heath, AC, Larson-Prior, L, Marcus, D, Michalareas, G, Moeller, S, Oostenveld, R, Petersen, SE, Prior, F, Schlaggar, BL, Smith, SM, Snyder, AZ, Xu, J & Yacoub, E 2012, 'The Human Connectome Project: A data acquisition perspective', NeuroImage, vol. 62, no. 4, pp. 2222-2231. https://doi.org/10.1016/j.neuroimage.2012.02.018

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abstract = "The Human Connectome Project (HCP) is an ambitious 5-year effort to characterize brain connectivity and function and their variability in healthy adults. This review summarizes the data acquisition plans being implemented by a consortium of HCP investigators who will study a population of 1200 subjects (twins and their non-twin siblings) using multiple imaging modalities along with extensive behavioral and genetic data. The imaging modalities will include diffusion imaging (dMRI), resting-state fMRI (R-fMRI), task-evoked fMRI (T-fMRI), T1- and T2-weighted MRI for structural and myelin mapping, plus combined magnetoencephalography and electroencephalography (MEG/EEG). Given the importance of obtaining the best possible data quality, we discuss the efforts underway during the first two years of the grant (Phase I) to refine and optimize many aspects of HCP data acquisition, including a new 7T scanner, a customized 3T scanner, and improved MR pulse sequences.",

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note = "Funding Information: We thank the entire WU-Minn HCP consortium team for their excellent efforts that have contributed directly or indirectly to the plans described in this manuscript. Funded in part by the Human Connectome Project ( 1U54MH091657 ) from the 16 NIH Institutes and Centers that Support the NIH Blueprint for Neuroscience Research, and by the McDonnell Center for Systems Neuroscience at Washington University . Members of the WU-Minn HCP Consortium are listed at http://www.humanconnectome.org/about/hcp-investigators.html and http://www.humanconnectome.org/about/hcp-colleagues.html . ",

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AU - Van Essen, D. C.

AU - Ugurbil, K.

AU - Auerbach, E.

AU - Barch, D.

AU - Behrens, T. E.J.

AU - Bucholz, R.

AU - Chang, A.

AU - Chen, L.

AU - Corbetta, M.

AU - Curtiss, S. W.

AU - Della Penna, S.

AU - Feinberg, D.

AU - Glasser, M. F.

AU - Harel, N.

AU - Heath, A. C.

AU - Larson-Prior, L.

AU - Marcus, D.

AU - Michalareas, G.

AU - Moeller, S.

AU - Oostenveld, R.

AU - Petersen, S. E.

AU - Prior, F.

AU - Schlaggar, B. L.

AU - Smith, S. M.

AU - Snyder, A. Z.

AU - Xu, J.

AU - Yacoub, E.

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The Human Connectome Project: A data acquisition perspective

Abstract

Bibliographical note

Keywords

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